![noncompressible calcified vessel meaning noncompressible calcified vessel meaning](https://image.slidesharecdn.com/roleofmdctincoronarycalcifications-160423042503/95/role-of-mdct-in-coronary-calcifications-dr-muhammad-bin-zulfiqar-15-638.jpg)
Its validity has been reported elsewhere ( 14, 15). Ankle systolic blood pressure and ABI were evaluated in all the recruited patients before endovascular therapy with the use of the automated oscillometric device provided by OMRON COLIN Co., Ltd. Patients were excluded if they were considered to be poor candidates for angiography and subsequent revascularization as a result of severe comorbidities including hemodynamic risk or difficulty having supine rest during the intervention or they refused the intervention. The indication of endovascular therapy was judged by consensus among vascular specialists including vascular surgeons.
![noncompressible calcified vessel meaning noncompressible calcified vessel meaning](https://thumbs.dreamstime.com/b/arterial-media-calcification-vessels-human-brain-29281327.jpg)
Once patients were diagnosed as CLI, endovascular therapy was used as the first-line procedure for revascularization, within the recommendations in TASC (II). The diagnosis and management of CLI were compliant with TASC ( 12) or its revised consensus, TASC II ( 1). Elevation of these measurements might be more common in CLI patients than expected.Īll the referred patients were evaluated for limb ischemia by angiography.
#NONCOMPRESSIBLE CALCIFIED VESSEL MEANING SKIN#
A previous clinical study disclosed in patient characteristics that about half of the recruited CLI patients with ischemic skin lesions had ankle systolic blood pressure higher than 70 mmHg ( 13).
![noncompressible calcified vessel meaning noncompressible calcified vessel meaning](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2F1471-2369-14-120/MediaObjects/12882_2013_Article_550_Fig2_HTML.jpg)
Although TransAtlantic Inter-Society Consensus (TASC) ( 12), a worldwide clinical guideline for PAD, and its revised consensus TASC II ( 1) acknowledge the validity of using ankle systolic blood pressure and ABI in the detection of CLI, little is known about the distribution of these measurements and the influence of comorbidities on these measurements in CLI patients. It is associated with an extremely poor prognosis for both survival and limb salvage its prompt diagnosis and following revascularization are therefore important. CLI is a manifestation of PAD that describes patients with chronic ischemic rest pain or with ischemic skin lesions, either ulcers or gangrene. No clinical data are so far available, however, about whether these falsely elevated measurements could be similarly observed in patients with critical limb ischemia (CLI). Their usefulness in clinical practice is now widely recognized. Furthermore, ABI is also known as an independent prognostic risk factor for fatal and nonfatal cardiovascular disease and all-cause mortality in a general population ( 3– 5), as well as in diabetic patients ( 6) and in patients with end-stage kidney disease receiving hemodialysis ( 7).
![noncompressible calcified vessel meaning noncompressible calcified vessel meaning](https://www.aimspress.com/aimspress-data/aimsmoles/2020/3/PIC/molsci-07-03-009-g009.jpg)
Because of their predictive capability and noninvasiveness, these measurements are recommended for screening and determining PAD in many clinical settings ( 2). ABI ≤0.90 in symptomatic individuals, for example, is approximately 95% sensitive in detecting arteriogram-positive PAD and almost 100% specific in identifying healthy individuals ( 1). A reduced value of these measurements is caused by hemodynamically significant arterial stenosis and therefore indicates the presence of peripheral arterial disease (PAD). Ankle systolic blood pressure and its ratio to brachial systolic blood pressure, that is, ankle-brachial systolic pressure index (ABI), reflect arterial hemodynamics in lower extremity.